Utility of Lymphoblastoid Cell Lines for Induced Pluripotent Stem Cell Generation

Figure 8

Clustering properties of LCLs and their reprogrammed iPSCs (a) Hierarchical clustering analysis and PCA in LCLs based on all genes detected as expressed during LCL-to-iPSC reprogramming. (b) Hierarchical clustering analysis and PCA in generated iPSCs based on all genes detected as expressed during LCL-to-iPSC reprogramming. ^#The donors of LCL-1 and LCL-3 were diagnosed with sporadic Parkinson’s disease. The donors of LCL-2, LCL-4, LCL-5, and LCL-6 were healthy. The donors of LCL-3 and LCL-4 were first-degree relatives whereas all other donors were unrelated.

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