Semaphorin 3A Shifts Adipose Mesenchymal Stem Cells towards Osteogenic Phenotype and Promotes Bone Regeneration In Vivo

Figure 5

engrafted PLGA scaffold increases bone repair in the calvarial defect model. (a) Representative images showing bone defect healing after 4 or 16 weeks of treatments. Control indicates that defects received nothing; , , and indicate that defects implanted with ASC, , and , respectively. BV/TV (b) and trabecular thickness (c) of the regenerated bone 16 weeks after transplantation. Mean ± SD, , and . BV, bone volume; TV, total volume.

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