Stem Cells International / 2016 / Article / Tab 2 / Research Article
Differential Proteomic Analysis of Human Placenta-Derived Mesenchymal Stem Cells Cultured on Normal Tissue Culture Surface and Hyaluronan-Coated Surface Table 2 Stress-responsive, intracellular signaling proteins. H, heavy; L, light.
Category
Protein IDs Protein names Gene name Normalized ratios Function Reference H/L H/L H/L OTCS OCHA OCHA Signal transduction P62070; P10301 Ras-related protein R-Ras2; Ras-related protein R-Ras RRAS2; RRAS 1.4273 0.6302 NA Intracellular signaling [37 , 38 ] Protein folding/stress P46734; P52564 Dual specificity mitogen-activated protein kinase kinase 3; dual specificity mitogen-activated protein kinase kinase 6 MAP2K3; MAP2K6 1.2744 0.6174 ND Environmental stress [39 ] STRING Metabolism P43490 Nicotinamide phosphoribosyltransferase NAMPT 0.47879 2.2273 1.3492 Interaction with SIRT1 [40 ] Protein folding/stress P13667 Protein disulfide-isomerase A4 PDIA4 0.83829 2.0283 1.46726 Protein folding [41 , 42 ] Protein folding/stress P14625; Q58FF3 Endoplasmin HSP90B1 0.98611 1.8484 1.4263 Protein degradation [41 ] Protein folding/stress Q9Y4L1 Hypoxia upregulated protein 1 HYOU1 0.894 1.73295 1.2425 Protein folding [41 ] Protein folding/stress P11021 78 kDa glucose-regulated protein HSPA5 0.873 1.6583 1.2862 Protein folding [41 , 42 ] Signal transduction P63098; Q96LZ3 Calcineurin subunit B type 1 PPP3R1 NA 1.6969 ND Ca2+ regulation STRING Signal transduction P37235; P84074; P61601 Hippocalcin-like protein 1; neuron-specific calcium-binding protein hippocalcin HPCAL1; HPCA NA 2.6682 2.5190 Ca2+ regulation STRING Signal transduction Q6UXH1 Cysteine-rich with EGF-like domain protein 2 CRELD2 NA 1.7720 1.5329 Ca2+ regulation STRING Protein biosynthesis/degradation P45974 Ubiquitin carboxyl-terminal hydrolase 5 USP5 1.042 1.5207 2.1350 p53 degradation [43 ] Protein biosynthesis/degradation P61201 COP9 signalosome complex subunit 2 COPS2 NA 1.7612 1.2704 p53 degradation [44 , 45 ] Protein biosynthesis/degradation Q9UNS2 COP9 signalosome complex subunit 3 COPS3 NA 3.7121 NA p53 degradation [45 ] Signal transduction Q63ZY3 KN motif and ankyrin repeat domain-containing protein 2 KANK2 ND 2.0810 0.801 Binding of ankyrin domain to CD44 [46 , 47 ]
