Comparative Analysis of Human Mesenchymal Stem Cells from Umbilical Cord, Dental Pulp, and Menstrual Blood as Sources for Cell Therapy
Table 1
Comparison of surface markers of UC-MSCs, DP-MSCs, and MB-MSCs.
CD29
CD44
CD90
CD14
CD34
CD45
UC-MSCs
P2
99.0 ± 0.3
98.7 ± 0.6
97.5 ± 0.6#
0.7 ± 0.2
0.3 ± 0.3
0.6 ± 0.2
P6
97.3 ± 1.0
98.1 ± 1.1
97.3 ± 0.6
0.4 ± 0.1
1.6 ± 0.5
1.3 ± 0.2
P10
97.2 ± 0.8
97.6 ± 0.9
86.2 ± 1.8
0.9 ± 0.3
0.8 ± 0.3
0.7 ± 0.2
DP-MSCs
P2
99.1 ± 0.2
99.7 ± 0.2
96.9 ± 0.5
0.4 ± 0.1
0.6 ± 0.2
0.3 ± 0.2
P6
96.8 ± 0.7
99.2 ± 0.2#
99.6 ± 0.3
0.5 ± 0.2
0.9 ± 0.3#
0.7 ± 0.2
P10
95.5 ± 0.6
97.1 ± 0.6
98.5 ± 0.5
0.5 ± 0.2
0.3 ± 0.2
0.4 ± 0.2
MB-MSCs
P2
97.4 ± 1.4#
98.6 ± 0.7#
97.5 ± 0.9#
0.6 ± 0.2#
0.2 ± 0.1#
0.3 ± 0.2#
P6
98.5 ± 0.5#
98.4 ± 0.7#
97.9 ± 0.7#
0.7 ± 0.2#
0.4 ± 0.2#
0.8 ± 0.3#
P10
75.4 ± 1.4
81.3 ± 0.8
80.6 ± 1.4
1.1 ± 0.2
0.8 ± 0.1
4.5 ± 0.6
Compared with P6 of corresponding MSCs; #compared with P10 of corresponding MSCs; compared with DP-MSCs at corresponding passage; compared with MB-MSCs at corresponding passage, . More than 95% indicates positive; less than 5% indicates negative. UC-MSCs: umbilical cord mesenchymal stem cells; DP-MSCs: dental pulp mesenchymal stem cells; MB-MSCs: menstrual blood mesenchymal stem cells; P: passage.
