Improved Protective Effect of Umbilical Cord Stem Cell Transplantation on Cisplatin-Induced Kidney Injury in Mice Pretreated with Antithymocyte Globulin
Gene expression of inflammatory and oxidative proteins in kidneys of 8–12-week-old male BALB/cOlaHsd mice after cisplatin-induced AKI treated with ATG and/or MSCs. Bars represent alterations in expression of cytokines, inflammatory, and oxidative proteins as measured by RT-PCR in kidney tissues of sacrificed mice. Results are expressed as mean ± SEM. ANOVA followed by Duncun multicomparison test: ; ; SAA3: serum amyloid A3, HO-1: heme oxygenase-1, GPx: glutathione peroxidase, CAT: catalase, SOD-1: superoxide dismutase-1, SOD-2: superoxide dismutase 2, IL-1β: interleukin 1β, TGF-β: transforming growth factor β, and ICAM-1: intercellular adhesion molecule 1.
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