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Stem Cells International
Volume 2016, Article ID 3598542, 8 pages
http://dx.doi.org/10.1155/2016/3598542
Research Article

Targeted Inhibition of the miR-199a/214 Cluster by CRISPR Interference Augments the Tumor Tropism of Human Induced Pluripotent Stem Cell-Derived Neural Stem Cells under Hypoxic Condition

1Key Laboratory for Major Obstetric Diseases of Guangdong Province, Key Laboratory of Reproduction and Genetics of Guangdong Higher Education Institutes, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510150, China
2Laboratory of Membrane Biology, New York Blood Center, New York, NY 10065, USA
3Department of Gastrointestinal Surgery, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510150, China
4Department of Biological Sciences, National University of Singapore, Singapore 117543
5Department of Genetic Medicine, Weill Cornell Medical College, New York, NY 10065, USA

Received 23 August 2016; Revised 15 October 2016; Accepted 25 October 2016

Academic Editor: Gary E. Lyons

Copyright © 2016 Yumei Luo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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