Cell Fate and Differentiation of Bone Marrow Mesenchymal Stem Cells

Table 1

The proteins regulate adipogenesis and osteoblastogenesis.

Number	Protein(s)	Function	Assay	Reference(s)
1	Msx2	Adipogenesis↓; osteoblastogenesis↑	In vitro	[66]
2	Dlk1/Pref-1	Adipogenesis↓; osteoblastogenesis↑	In vitro	[67]
3	TAZ	Adipogenesis↓; osteoblastogenesis↑	Zebrafish; in vitro	[68]
4	Wnt10b	Adipogenesis↓; osteoblastogenesis↑	Knockout mice; transgenic mice	[69]
5	LIP	Adipogenesis↓; osteoblastogenesis↑	In vitro	[70]
6	Dec1	Adipogenesis↓; osteoblastogenesis↑	In vitro	[71]
7	Hemooxygenase-1	Adipogenesis↓; osteoblastogenesis↑	In vitro	[72]
8	ID4	Adipogenesis↓; osteoblastogenesis↑	Knockout mice	[73]
9	Maf	Adipogenesis↓; osteoblastogenesis↑	Knockout mice	[74]
10	Pkd1	Adipogenesis↓; osteoblastogenesis↑	Knockout mice	[75]
11	sFRP-1	Adipogenesis↑; osteoblastogenesis↓	In vitro	[76]
12	ZFP467	Adipogenesis↑; osteoblastogenesis↓	In vivo injection	[77]
13	GIT2	Adipogenesis↓; osteoblastogenesis↑	Knockout mice	[78]
14	Wnt6	Adipogenesis↓; osteoblastogenesis↑	In vitro	[79]
15	Wnt10a	Adipogenesis↓; osteoblastogenesis↑	In vitro	[79]
16	VEGF	Adipogenesis↓; osteoblastogenesis↑	Knockout mice	[80]
17	Semaphorin 3A	Adipogenesis↓; osteoblastogenesis↑	Knockout mice	[81]
18	TLE3	Adipogenesis↑; osteoblastogenesis↓	In vitro	[19]
19	S100a16	Adipogenesis↑; osteoblastogenesis↓	In vitro	[82]
20	mTORC2	Adipogenesis↓; osteoblastogenesis↑	In vitro	[83]
21	Adiponectin	Adipogenesis↓; osteoblastogenesis↑	Knockout mice	[84]
22	Cysteine dioxygenase type 1	Adipogenesis↑; osteoblastogenesis↓	In vitro	[85, 86]
23	MYSM1	Adipogenesis↓; osteoblastogenesis↑	Knockout mice	[87]