Cancer Stem Cell Plasticity as Tumor Growth Promoter and Catalyst of Population Collapse

Table 1

Summary of model parameters.

Parameter	Description	Nominal value
	Nonstem cancer cell proliferation capacity	10
	Probability of spontaneous death of nonstem cancer cell	1%
	Probability of symmetric division of cancer stem cell	1%
	Differentiation probability	1%
	Dedifferentiation probability	1%
	Proliferation probability	1/24
	Migration probability if there is no proliferation	15/24
	Radioresistance of quiescent cell, that is, for a cell with no available space in the neighborhood	0.5
	Radioresistance of cancer stem cell	0.1376
	Parameter of linear-quadratic radiation response model, 1/Gy	0.3859
	Parameter of linear-quadratic radiation response model, 1/Gy^2	0.01148
	Radiation dose, Gy	2