MicroRNAs: From Female Fertility, Germ Cells, and Stem Cells to Cancer in Humans

Figure 4

MiRNAs in human sperm, mature oocytes, and embryos, important for fertilization and embryo development [75–80]. Some miRNAs identified in sperm are contributed to the oocyte during the fertilization process and are involved in embryogenesis. Abundant maternal miRNAs of Let-7 family are involved in oocyte-to-embryo transition and are replaced by embryonic miRNAs, related to pluripotency.