Review Article
MicroRNAs: From Female Fertility, Germ Cells, and Stem Cells to Cancer in Humans
Table 1
MiRNAs regulating pluripotency and differentiation of hESCs.
| Genes related to pluripotency | References | OCT4 | NANOG | SOX2 | KLF4 | LEFTY | NR2F2 |
| Maintenance of pluripotency | | miR-203 | miR-203 | | | | | [82] |
| Regulation of stem cell renewal and differentiation | | | miR-200c | | | | | [83] |
| Delay of differentiation, balance between differentiation and pluripotency | | | | | | miR-302s | | [84] |
| Low in self-renewal and high during differentiation | | miR-145 | | miR-145 | miR-145 | | | [85] |
| Regulation of cell cycle genes in pluripotent stem cells | | miR-302a | | miR-302a | | | | [86] |
| Balance between pluripotency and differentiation, NR2F2 critical for neural gene activation | | miR-302 | | | | | miR-302 | [87] |
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