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Stem Cells International
Volume 2016, Article ID 4062789, 13 pages
http://dx.doi.org/10.1155/2016/4062789
Research Article

Umbilical Cord-Derived Mesenchymal Stem Cells Suppress Autophagy of T Cells in Patients with Systemic Lupus Erythematosus via Transfer of Mitochondria

1Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu 210008, China
2Department of Rheumatology and Immunology, Drum Tower Clinical Medical College of Nanjing Medical University, Nanjing, Jiangsu 210008, China
3Department of Rheumatology and Immunology, The 3rd Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, China

Received 24 May 2016; Revised 5 November 2016; Accepted 10 November 2016

Academic Editor: Armand Keating

Copyright © 2016 Jinyun Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [7 citations]

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  • Zhongfang Zhao, Ying Han, Zhihui Zhang, Wenwen Li, Xiaoli Ji, Xiaodan Liu, Jianqiu Jin, Si Xu, Hongmei Cui, Zhe Cheng, Qian Wang, Xing Wang, Xiang Guo, Yixiang Wang, and Hongwei Liu, “Total glucosides of paeony improves the immunomodulatory capacity of MSCs partially via the miR-124/STAT3 pathway in oral lichen planus,” Biomedicine & Pharmacotherapy, vol. 105, pp. 151–158, 2018. View at Publisher · View at Google Scholar
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  • Jingyu Wang, Heyangzi Li, Ying Yao, Tengfei Zhao, Ying-ying Chen, Yue-liang Shen, Lin-lin Wang, and Yongjian Zhu, “Stem cell-derived mitochondria transplantation: a novel strategy and the challenges for the treatment of tissue injury,” Stem Cell Research & Therapy, vol. 9, no. 1, 2018. View at Publisher · View at Google Scholar
  • Xianhua Gui, Hongwei Chen, Hourong Cai, Lingyun Sun, and Luo Gu, “Leptin promotes pulmonary fibrosis development by inhibiting autophagy via PI3K/Akt/mTOR pathway,” Biochemical and Biophysical Research Communications, vol. 498, no. 3, pp. 660–666, 2018. View at Publisher · View at Google Scholar
  • Ruixia Deng, Anna Hing Yee Law, Jiangang Shen, and Godfrey Chi-Fung Chan, “Mini Review: Application of Human Mesenchymal Stem Cells in Gene and Stem Cells Therapy Era,” Current Stem Cell Reports, 2018. View at Publisher · View at Google Scholar
  • Carlos Vaamonde-García, and María J López-Armada, “Role of mitochondrial dysfunction on rheumatic diseases,” Biochemical Pharmacology, 2019. View at Publisher · View at Google Scholar