Umbilical Cord-Derived Mesenchymal Stem Cells Suppress Autophagy of T Cells in Patients with Systemic Lupus Erythematosus via Transfer of Mitochondria

Figure 2

T cells from SLE patients had overactivated autophagy. PBMCs were stimulated with or without anti-CD3/CD28 antibodies (3 μg/mL) for 3 days. In vitro experiments were performed in triplicate. ((a), (b)) Basal autophagy of T cells from SLE patients () was higher than that from healthy controls () and further increased after anti-CD3/28 stimulation. The number of T cells was normalized to mode. ;  ;  .

(a)

(b)