Magnetic Nanoparticles for Targeting and Imaging of Stem Cells in Myocardial Infarction

Figure 2

In vivo visualization immediately before and after IFP-MSC injection. Long-axis SSFP MRI view of left ventricle before (a) and after (b) transcatheter injection of 4 × 106 IFP-labeled MSCs into the infarct at the apex (arrows) and adjoining normal myocardium (arrowhead). Delayed enhancement MRI highlights areas of nonviable infarcted myocardium using the same view as above, before (c) and after (d) injection of IFP-labeled MSCs. MSCs appear dark against hyperenhanced infarct (reproduced with permission [27]).

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