Evaluating the Impact of Human Amnion Epithelial Cells on Angiogenesis
H&E staining and vWF immunohistochemistry in neonatal mouse lung tissue. (a) Hyperoxia-induced lung injury mice had simplified lung structure and enlarged alveoli, and term hAEC treatment improved lung structure. (b) The number of vessels (diameter < 50 μm) decreased in hyperoxia-injured animals compared with normoxia animals (). Term hAEC administration restored the number of small pulmonary vessels in hyperoxia-induced lung injury animals (). (c) The representative images for vWF immunohistochemistry in mouse lung tissues (, ).