Survivin Improves Reprogramming Efficiency of Human Neural Progenitors by Single Molecule OCT4

Figure 4

AP positive numbers in Survivin overexpression or Survivin knockdown in the reprogramming of NPCs. (a) AP positive numbers of 1F-OCT4, mock (vector control), and Survivin overexpression on 3.5 cm diameter well from the left to right; (b) AP positive numbers of 1F-OCT4, nonsilence, and Survivin-RNAi on the same size dishes (from the left to right). A representative experiment is shown in the left panels. Counting AP+ colonies in the same experiment, mean values + SD are shown in the right panels. (c) The relative expression of Survivin in mRNA level.

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