Human iPSC for Therapeutic Approaches to the Nervous System: Present and Future Applications

Table 2

Therapeutic agents delivered by SC for the treatment of HGG.

Agent delivered	Type of stem cells
	ESC	NSC	MSC
Cytokines	Mda-7/IL24, TRAIL	IL-4, IL-12, IL-23, TRAIL +/− BMZ, and S-TRAIL +/− MIR/TMZ	IL-2, IL-12, IL-18, INFα, INF-β, and TRAIL +/− PI3KI
Enzyme/prodrug		Tk/GCV, CD/5FC +/− IFNβ	Tk/GCV
Viral particles		Mutant HSV-1, CRAd-survivin	CRAd-survivin, CRAd-CXCR4, and CRAd-Rb
Metalloproteinases		PEX
Antibodies			EGFRvIII
Nanoparticles			Ferrociphenol lipid