Cardiac Niche Influences the Direct Reprogramming of Canine Fibroblasts into Cardiomyocyte-Like Cells

Figure 6

ciCLMs in vivo injection. (a) Immunofluorescence analysis for GFP expression ciCLMs after cell sorting for GFP and before injections. (b) 2 × 10⁵ GFP positive cells were injected directly in the heart of 2-day-old pups. After 14 days pups were sacrificed and heart sections were prepared and double stained with antibodies against dystrophin (red) and GFP (green). (c) Average number of ciCLMs GFP positive cells per section; . (d) Double staining with antibodies against myosin heavy chain (red) and GFP (green).

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