Inhibition of JAK-STAT ERK/MAPK and Glycogen Synthase Kinase-3 Induces a Change in Gene Expression Profile of Bovine Induced Pluripotent Stem Cells

Table 1

Summary of the different treatments used to evaluate the effect of pathway inhibition on gene expression profiles. 5-Azacytidine (5-AzaC), glycogen synthase kinase-3 (GSK-3), extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinase (MAPK), and DNA methyltransferases (DNMTs).

	GSK3	ERK/MAPK	DNMT (Di)	GSK3 + ERK/MAPK (2i)	GSK3 + DNMT	ERK/MAPK + DNMT	2i + Di	Control
Bio	1 µM			1 µM	1 µM		1 µM
SC1		0.5 µM		0.5 µM		0.5 µM	0.5 µM
5-AzaC			5 µM		5 µM	5 µM	0.5 µM