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Stem Cells International
Volume 2016, Article ID 5161248, 12 pages
http://dx.doi.org/10.1155/2016/5161248
Research Article

Neurotrophic Effect of Adipose Tissue-Derived Stem Cells on Erectile Function Recovery by Pigment Epithelium-Derived Factor Secretion in a Rat Model of Cavernous Nerve Injury

1Department of Urology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China
2Department of Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China
3Reproductive Medicine Research Center, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou 510655, China
4Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China

Received 4 April 2015; Revised 14 August 2015; Accepted 23 August 2015

Academic Editor: Yang D. Teng

Copyright © 2016 Xin Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [13 citations]

The following is the list of published articles that have cited the current article.

  • Ezzat A. Ismail, and Ahmed I. El-Sakka, “Innovative trends and perspectives for erectile dysfunction treatment: A systematic review,” Arab Journal of Urology, 2016. View at Publisher · View at Google Scholar
  • Mohammad Ayodhia Soebadi, Uros Milenkovic, Emmanuel Weyne, Fabio Castiglione, and Maarten Albersen, “Stem Cells in Male Sexual Dysfunction: Are We Getting Somewhere?,” Sexual Medicine Reviews, 2016. View at Publisher · View at Google Scholar
  • Qiyun Yang, Xiaoyan Liang, Yuanyuan Zhang, Chunhua Deng, Xin Chen, Dayu Han, Guihua Liu, Tao Zheng, Heng Zhang, Yanan Shi, Jun Bian, Xiangzhou Sun, and Kai Xia, “Transplantation of human urine-derived stem cells transfected with pigment epithelium-derived factor to protect erectile function in a rat model of cavernous nerve injury,” Cell Transplantation, vol. 25, no. 11, pp. 1987–2001, 2016. View at Publisher · View at Google Scholar
  • Takanori Matsui, and Sho-Ichi Yamagishi, “Pigment epithelium-derived factor: A novel therapeutic target for cardiometabolic diseases and related complications,” Current Medicinal Chemistry, vol. 25, no. 13, pp. 1480–1500, 2017. View at Publisher · View at Google Scholar
  • R. El Osta, V. Decot, D. Bensoussan, J.F. Stoltz, P. Eschwege, and J. Hubert, “Traitement par les cellules souches de la dysfonction érectile d’origine diabétique : état des lieux,” Progrès en Urologie, 2017. View at Publisher · View at Google Scholar
  • Shuyun Zhang, and Baolin Shi, “Erythropoietin Modification Enhances the Protection of Mesenchymal Stem Cells on Diabetic Rat-Derived Schwann Cells: Implications for Diabetic Neuropathy,” BioMed Research International, vol. 2017, pp. 1–11, 2017. View at Publisher · View at Google Scholar
  • Dimitrios Memmos, Ioannis Mykoniatis, Ioannis Vakalopoulos, Chrysovalantis Toutziaris, and Georgios Dimitriadis, “Stem cell therapy in erectile dysfunction: science fiction or realistic treatment option?,” Hormones, vol. 17, no. 3, pp. 315–320, 2018. View at Publisher · View at Google Scholar
  • Xiao Tian, Tongsong Wang, Songmei Zhang, Qian Wang, Xiaoli Hu, Cheng Ge, Lixin Xie, and Qingjun Zhou, “PEDF Reduces the Severity of Herpetic Simplex Keratitis in Mice,” Investigative Opthalmology & Visual Science, vol. 59, no. 7, pp. 2923, 2018. View at Publisher · View at Google Scholar
  • Biljana Musicki, Anil K. Bhunia, Serkan Karakus, and Arthur L. Burnett, “S-nitrosylation of NOS pathway mediators in the penis contributes to cavernous nerve injury-induced erectile dysfunction,” International Journal of Impotence Research, 2018. View at Publisher · View at Google Scholar
  • Uros Milenkovic, Maarten Albersen, and Fabio Castiglione, “The mechanisms and potential of stem cell therapy for penile fibrosis,” Nature Reviews Urology, 2018. View at Publisher · View at Google Scholar
  • Serap Gur, Asim B Abdel-Mageed, Suresh C. Sikka, and Wayne J.G. Hellstrom, “Advances in stem cell therapy for erectile dysfunction,” Expert Opinion on Biological Therapy, vol. 18, no. 11, pp. 1137–1150, 2018. View at Publisher · View at Google Scholar
  • Botao Yu, Changjing Wu, Feng Qin, Jiuhong Yuan, and Tao Li, “Advances in gene therapy for erectile dysfunction: Promises and challenges,” Current Gene Therapy, vol. 18, no. 6, pp. 351–365, 2018. View at Publisher · View at Google Scholar
  • Yun Xie, Chi Zhang, Cuncan Deng, Linyan Lv, Yuanyuan Zhang, Junhong Deng, Bin Ouyang, Chunhua Deng, Jiahui Yao, and Guihua Liu, “Extracellular Vesicles From Human Urine-Derived Stem Cells Ameliorate Erectile Dysfunction in a Diabetic Rat Model by Delivering Proangiogenic MicroRNA,” Sexual Medicine, 2019. View at Publisher · View at Google Scholar