Research Article

Phenotypic and Functional Characterization of Mesenchymal Stem/Multipotent Stromal Cells from Decidua Basalis of Human Term Placenta

Table 6

The expression of growth factors and growth factor receptors in DBMSCs as determined by real-time PCR. Each experiment was performed using DBMSCs from passages three of five individual placentae.

Growth factor receptorsResultsGrowth factor/receptors and immune moleculeResults

PDGFRA: platelet-derived growth factor receptor α+++FPR2: formyl peptide receptor 2++
PDGFRB: platelet-derived growth factor receptor β+++OGFR: opioid growth factor receptor (OGFR)+++
FGFR4: fibroblast growth factor receptor 2+++IGF1R: insulin-like growth factor 1+++
FGFR2: fibroblast growth factor receptor 4++CSF2RB: Colony stimulating factor 2 receptor, β+++
IFNGR1: interferon gamma receptor 1+++EGFR: epidermal growth factor receptor+++
IFNGR2: interferon gamma receptor 2+++NPTN: neuroplastin+++
IFNAR1: interferon (alpha, beta, and omega) receptor 1+++HRH4: histamine receptor H4+
IFNAR2: interferon (alpha, beta, and omega) receptor 2+++FLT4: fms-related tyrosine kinase 4+++
NGFR: nerve growth factor receptor+++FLT1: fms-related tyrosine kinase 1 (vascular endothelial growth factor)+++
KDR: kinase insert domain receptor (type III receptor tyrosine kinase)++TNFRSF1A: tumor necrosis factor receptor superfamily member 1A+++
IFNK: interferon, kappa+TNFRSF1B: tumor necrosis factor receptor superfamily member 1B+++
FGFR1: fibroblast growth factor receptor 1+++MET: met protooncogene (hepatocyte growth factor receptor)+++
FGFR3: fibroblast growth factor receptor 3+EGF: epidermal growth factor
TGFBR1: transforming growth factor beta receptor 1+++Indoleamine 2,3-dioxygenase+
TGFBR2: transforming growth factor beta receptor II+++

Note. (−) no expression; (+) weak expression; (++) moderate expression; (+++) strong expression of mRNA.