Lavandula angustifolia Extract Improves the Result of Human Umbilical Mesenchymal Wharton’s Jelly Stem Cell Transplantation after Contusive Spinal Cord Injury in Wistar Rats

Figure 1

Administration of L. angustifolia extract improves motor and sensory function impairment in the rat spinal cord contusion model treated with HUMSCs. Administration of L. angustifolia extract (i.p.) daily for 14 consecutive days after injury significantly improved BBB scores (a) and sensory function (with decreased delayed response in the hot-water test) in HUMSCs treated animals (b). Data are represented as mean ± SEM. (a) , ,  and show significant differences of BBB scores between HUMSCs, HUMSCs + Lav 100, 200, and 400, and SCI group (control 1) (, , and , resp.). , , and show significant differences of BBB scores between HUMSCs + Lav 100, 200, and 400, and HUMSCs treated group (control 2) (, , and , resp.). (b) and show significant differences of sensory function between HUMSCs and SCI group (control 1) ( and , resp.). and show significant differences of sensory function between HUMSCs + Lav 400 and HUMSCs treated group (control 2) ( and , resp.). , , and show significant differences of sensory function between HUMSCs + Lav 400 and SCI group (control 1) (, , and , resp.).

(a) Locomotion activity

(b) Sensory function