tPA-MMP-9 Axis Plays a Pivotal Role in Mobilization of Endothelial Progenitor Cells from Bone Marrow to Circulation and Ischemic Region for Angiogenesis

<div>Proposed mechanisms. The proposed rescue model of bone marrow cells (BMC) transplantation on enhancing angiogenesis in matrix metalloproteinase- (MMP-) 9 deficient mice with critical limb ischemia. EPC = endothelial progenitor cells; SDF-1<i>α</i> = stromal cell-derived factor-1<i>α</i>; ECM = extracellular matrix.</div>

Stem Cells International

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Figure 16

Figure 16: tPA-MMP-9 Axis Plays a Pivotal Role in Mobilization of Endothelial Progenitor Cells from Bone Marrow to Circulation and Ischemic Region for Angiogenesis 

Figure 16 | tPA-MMP-9 Axis Plays a Pivotal Role in Mobilization of Endothelial Progenitor Cells from Bone Marrow to Circulation and Ischemic Region for Angiogenesis 