Research Article
The Effect of Culture on Human Bone Marrow Mesenchymal Stem Cells: Focus on DNA Methylation Profiles
Table 1
Percentage and ratio of CGIs reversing the methylation status in culture.
| | | Total CGIs | Promoter CGIs | Inside CGIs | | Number of CGIs | % reversal | Ratio met/dem. | % reversal | Ratio met/dem. | % reversal | Ratio met/dem. |
| X chromosome | 665 | 33.20 | 0.9 | 33.80 | 1.15 | 32.90 | 0.91 | All autosomes | 23133 | 35.60 | 0.37 | 38.8 | 0.40 | 33.8 | 0.37 | Chromosome 20 | 737 | 31.40 | 0.44 | 39 | 0.40 | 29 | 0.49 | XCI genes | 189 | 30.10 | 1.59 | 28.50 | 1.20 | 30.20 | 2 | No XCI genes | 476 | 34.40 | 0.74 | 36.60 | 1.12 | 34.30 | 0.65 | Escaping genes | 26 | 38.40 | | | | | |
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for comparison of value in cells of the same superscripted letters.
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