Fate and Effect of Intravenously Infused Mesenchymal Stem Cells in a Mouse Model of Hepatic Ischemia Reperfusion Injury and Resection

Figure 1

Hepatocellulair injury. (a) Six hours after IRI and PH, the serum ALAT concentration was significantly lower in mice treated with MSC 2 hours before hepatic IRI and PH compared to their PBS control. (b) Serum ASAT concentration, six hours after reperfusion, was significantly lower in mice treated with MSC 2 hours before IRI and PH compared to their PBS controls. (c) Forty-eight hours after IRI and PH there were no significant differences in serum ALAT levels between mice treated with MSC or PBS. (d) Serum ASAT concentrations showed no significant differences forty-eight hours after IRI and PH between mice infused with MSC or PBS. (e) Forty-eight hours after IRI and PH, livers from mice treated with MSC showed no differences in amount of necrosis compared to their PBS controls. The data are expressed as means ± SEM (() versus their PBS controls).

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