Feasibility and Efficiency of Human Bone Marrow Stromal Cell Culture with Allogeneic Platelet Lysate-Supplementation for Cell Therapy against Stroke

Figure 2

Cell proliferative potential for PL or FCS medium. (a) shows the quantity of cultured cells in PL- or FCS-supplemented culture medium. Gray bars: cells cultured with sPL; white bars: cells cultured with mPL; striped bar: the cells cultured with FCS. Error bars: SD. Broken line: the quantity of seeded cells on a well (6000 cells). (b) shows the quantity of cultured cells in PL-supplemented culture medium. -axis: numbers of the platelet units in original PC. (c) showed the cell proliferation when cultured in CPC as a simulation of the clinical trials, the RAINBOW study. Broken line: 20 million cells as the target in the low dose group. Solid line: 50 million cells as the target in the high dose group.

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