Vitamin D and the Epithelial to Mesenchymal Transition

Figure 1

Scheme showing the mechanisms involved in the reciprocal regulation between 1,25(OH)₂D₃ and EMT in human colon cancer cells. Proteins and pathways displayed in blue are associated with an epithelial phenotype, while those shown in red are related with a mesenchymal phenotype. Blue and red lines are used to indicate induction or repression, respectively.