Mesenchymal Stem Cell-Derived Microvesicles Support Ex Vivo Expansion of Cord Blood-Derived CD34⁺ Cells

Table 1

miRNAs expressed in MSC-MVs that are involved in regulation of hematopoiesis.

miRNA	Function	Targets	Ref.
miR-125a	Maintenance of self-renewal and differentiation balance in HSPCs	Unknown	[22]
miR-29a	Regulation of early hematopoiesis and myeloid commitment	HBP1	[23]
miR-223	Regulation of progenitor cell proliferation and granulocyte function	Mef2c	[24]
miR-21	Regulation of myelopoiesis	SMAD7	[25]
miR-451	Regulation of erythropoiesis	GATA-2	[26]
miR-144	Regulation of erythropoiesis	Klfd	[27]
miR-150	Modulating early B lymphocyte differentiation	c-Myb	[28]
miR-126	Regulation of primitive erythropoiesis	Vcam-1	[29]
miR-196b	Regulation of myelopoiesis	HOXA9, MEIS1	[30]
miR-125b	Regulation of stem cell pool size	Unknown	[22]
miR-181	Modulating T lymphocyte differentiation	DUSP6	[31]
miR-424	Regulation of monocytopoiesis	NFI-A	[32]