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Stem Cells International
Volume 2016 (2016), Article ID 6756983, 7 pages
http://dx.doi.org/10.1155/2016/6756983
Research Article

Tumor Mesenchymal Stem-Like Cell as a Prognostic Marker in Primary Glioblastoma

1Department of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea
2Department of Neurosurgery, Seoul St. Mary’s Hospital, The Catholic University of Korea College of Medicine, 222 Banpo-daero, Seocho-gu, Seoul 137-701, Republic of Korea
3Department of Life Science, Hanyang University, 17 Haendang-dong, Seongdong-gu, Seoul 133-791, Republic of Korea
4Department of Radiology, Severance Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea

Received 4 November 2015; Revised 5 January 2016; Accepted 13 January 2016

Academic Editor: Abdel Kareem Azab

Copyright © 2016 Seon-Jin Yoon et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Dong, Q. Zhang, Q. Huang et al., “Glioma stem cells involved in tumor tissue remodeling in a xenograft model: laboratory investigation,” Journal of Neurosurgery, vol. 113, no. 2, pp. 249–260, 2010. View at Publisher · View at Google Scholar · View at Scopus
  2. J. Behnan, P. Isakson, M. Joel et al., “Recruited brain tumor-derived mesenchymal stem cells contribute to brain tumor progression,” STEM CELLS, vol. 32, no. 5, pp. 1110–1123, 2014. View at Publisher · View at Google Scholar · View at Scopus
  3. A. Golebiewska, S. Bougnaud, D. Stieber et al., “Side population in human glioblastoma is non-tumorigenic and characterizes brain endothelial cells,” Brain, vol. 136, no. 5, pp. 1462–1475, 2013. View at Publisher · View at Google Scholar · View at Scopus
  4. L. Li, J. Cole, and D. A. Margolin, “Cancer stem cell and stromal microenvironment,” Ochsner Journal, vol. 13, no. 1, pp. 109–118, 2013. View at Google Scholar · View at Scopus
  5. B. Mognetti, G. La Montagna, M. G. Perrelli, P. Pagliaro, and C. Penna, “Bone marrow mesenchymal stem cells increase motility of prostate cancer cells via production of stromal cell-derived factor-1α,” Journal of Cellular and Molecular Medicine, vol. 17, no. 2, pp. 287–292, 2013. View at Publisher · View at Google Scholar · View at Scopus
  6. L. da Silva Meirelles, P. C. Chagastelles, and N. B. Nardi, “Mesenchymal stem cells reside in virtually all post-natal organs and tissues,” Journal of Cell Science, vol. 119, part 11, pp. 2204–2213, 2006. View at Publisher · View at Google Scholar · View at Scopus
  7. S.-G. Kang, N. Shinojima, A. Hossain et al., “Isolation and perivascular localization of mesenchymal stem cells from mouse brain,” Neurosurgery, vol. 67, no. 3, pp. 711–720, 2010. View at Publisher · View at Google Scholar · View at Scopus
  8. F. F. Lang, T. Amano, N. Hata, J. Gumin, K. Aldape, and H. Colman, “Bone marrow-derived mesenchymal stem cells are recruited to and alter the growth of human gliomas,” Neuro-Oncology, vol. 9, p. 596, 2007. View at Google Scholar
  9. J. Kwak, H.-J. Shin, S.-H. Kim et al., “Isolation of tumor spheres and mesenchymal stem-like cells from a single primitive neuroectodermal tumor specimen,” Child's Nervous System, vol. 29, no. 12, pp. 2229–2239, 2013. View at Publisher · View at Google Scholar · View at Scopus
  10. H.-Y. Lim, K. M. Kim, B. K. Kim et al., “Isolation of mesenchymal stem-like cells in meningioma specimens,” International Journal of Oncology, vol. 43, no. 4, pp. 1260–1268, 2013. View at Publisher · View at Google Scholar · View at Scopus
  11. Y. G. Kim, S. Jeon, G.-Y. Sin et al., “Existence of glioma stroma mesenchymal stemlike cells in Korean glioma specimens,” Child's Nervous System, vol. 29, no. 4, pp. 549–563, 2013. View at Publisher · View at Google Scholar · View at Scopus
  12. B. H. Kong, H.-D. Shin, S.-H. Kim et al., “Increased in vivo angiogenic effect of glioma stromal mesenchymal stem-like cells on glioma cancer stem cells from patients with glioblastoma,” International Journal of Oncology, vol. 42, no. 5, pp. 1754–1762, 2013. View at Publisher · View at Google Scholar · View at Scopus
  13. A. Hossain, J. Gumin, F. Gao et al., “Mesenchymal stem cells isolated from human gliomas increase proliferation and maintain stemness of glioma stem cells through the IL-6/gp130/STAT3 pathway,” STEM CELLS, vol. 33, no. 8, pp. 2400–2415, 2015. View at Publisher · View at Google Scholar
  14. E. Bourkoula, D. Mangoni, T. Ius et al., “Glioma-associated stem cells: a novel class of tumor-supporting cells able to predict prognosis of human low-grade gliomas,” Stem Cells, vol. 32, no. 5, pp. 1239–1253, 2014. View at Publisher · View at Google Scholar · View at Scopus
  15. W. A. Freije, F. E. Castro-Vargas, Z. Fang et al., “Gene expression profiling of gliomas strongly predicts survival,” Cancer Research, vol. 64, no. 18, pp. 6503–6510, 2004. View at Publisher · View at Google Scholar · View at Scopus
  16. Y. Liang, M. Diehn, N. Watson et al., “Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme,” Proceedings of the National Academy of Sciences of the United States of America, vol. 102, no. 16, pp. 5814–5819, 2005. View at Publisher · View at Google Scholar · View at Scopus
  17. H. S. Phillips, S. Kharbanda, R. Chen et al., “Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis,” Cancer Cell, vol. 9, no. 3, pp. 157–173, 2006. View at Publisher · View at Google Scholar · View at Scopus
  18. R. G. W. Verhaak, K. A. Hoadley, E. Purdom et al., “Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1,” Cancer Cell, vol. 17, no. 1, pp. 98–110, 2010. View at Publisher · View at Google Scholar · View at Scopus
  19. K. Aldape, G. Zadeh, S. Mansouri, G. Reifenberger, and A. von Deimling, “Glioblastoma: pathology, molecular mechanisms and markers,” Acta Neuropathologica, vol. 129, no. 6, pp. 829–848, 2015. View at Publisher · View at Google Scholar
  20. R. Beroukhim, G. Getz, L. Nghiemphu et al., “Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma,” Proceedings of the National Academy of Sciences of the United States of America, vol. 104, no. 50, pp. 20007–20012, 2007. View at Publisher · View at Google Scholar · View at Scopus
  21. C. Brennan, H. Momota, D. Hambardzumyan et al., “Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations,” PLoS ONE, vol. 4, no. 11, Article ID e7752, 2009. View at Publisher · View at Google Scholar · View at Scopus
  22. R. Shen, Q. Mo, N. Schultz et al., “Integrative subtype discovery in glioblastoma using iCluster,” PLoS ONE, vol. 7, no. 4, Article ID e35236, 2012. View at Publisher · View at Google Scholar · View at Scopus
  23. M. Karsy, J. A. Neil, J. Guan, M. A. Mahan, H. Colman, and R. L. Jensen, “A practical review of prognostic correlations of molecular biomarkers in glioblastoma,” Neurosurgical Focus, vol. 38, no. 3, p. E4, 2015. View at Publisher · View at Google Scholar
  24. M. E. Hegi, A.-C. Diserens, T. Gorlia et al., “MGMT gene silencing and benefit from temozolomide in glioblastoma,” The New England Journal of Medicine, vol. 352, no. 10, pp. 997–1003, 2005. View at Publisher · View at Google Scholar · View at Scopus
  25. M. Sanson, Y. Marie, S. Paris et al., “Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas,” Journal of Clinical Oncology, vol. 27, no. 25, pp. 4150–4154, 2009. View at Publisher · View at Google Scholar · View at Scopus
  26. H. Nakamura, K. Makino, and J.-I. Kuratsu, “Molecular and clinical analysis of glioblastoma with an oligodendroglial component (GBMO),” Brain Tumor Pathology, vol. 28, no. 3, pp. 185–190, 2011. View at Publisher · View at Google Scholar · View at Scopus
  27. M. Mizoguchi, K. Yoshimoto, X. Ma et al., “Molecular characteristics of glioblastoma with 1p/19q co-deletion,” Brain Tumor Pathology, vol. 29, no. 3, pp. 148–153, 2012. View at Publisher · View at Google Scholar · View at Scopus
  28. B. H. Kong, J. H. Moon, Y.-M. Huh et al., “Prognostic value of glioma cancer stem cell isolation in survival of primary glioblastoma patients,” Stem Cells International, vol. 2014, Article ID 838950, 6 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  29. C. Isella, A. Terrasi, S. E. Bellomo et al., “Stromal contribution to the colorectal cancer transcriptome,” Nature Genetics, vol. 47, no. 4, pp. 312–319, 2015. View at Publisher · View at Google Scholar
  30. A. Calon, E. Lonardo, A. Berenguer-Llergo et al., “Stromal gene expression defines poor-prognosis subtypes in colorectal cancer,” Nature Genetics, vol. 47, no. 4, pp. 320–329, 2015. View at Publisher · View at Google Scholar
  31. R. Stupp, W. P. Mason, M. J. van den Bent et al., “Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma,” The New England Journal of Medicine, vol. 352, no. 10, pp. 987–996, 2005. View at Publisher · View at Google Scholar · View at Scopus
  32. D. N. Louis, H. Ohgaki, O. D. Wiestler et al., “The 2007 WHO classification of tumours of the central nervous system,” Acta Neuropathologica, vol. 114, no. 2, pp. 97–109, 2007. View at Publisher · View at Google Scholar · View at Scopus
  33. M. J. McGirt, K. L. Chaichana, M. Gathinji et al., “Independent association of extent of resection with survival in patients with malignant brain astrocytoma,” Journal of Neurosurgery, vol. 110, no. 1, pp. 156–162, 2009. View at Publisher · View at Google Scholar · View at Scopus
  34. C. M. Kramm, S. Wagner, S. Van Gool et al., “Improved survival after gross total resection of malignant gliomas in pediatric patients from the HIT-GBM studies,” Anticancer Research, vol. 26, no. 5, pp. 3773–3779, 2006. View at Google Scholar · View at Scopus
  35. M. Dominici, K. Le Blanc, I. Mueller et al., “Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement,” Cytotherapy, vol. 8, no. 4, pp. 315–317, 2006. View at Publisher · View at Google Scholar · View at Scopus
  36. A. Mathew, M. Pandey, and N. S. Murthy, “Survival analysis: caveats and pitfalls,” European Journal of Surgical Oncology, vol. 25, no. 3, pp. 321–329, 1999. View at Publisher · View at Google Scholar · View at Scopus
  37. S. Nobusawa, T. Watanabe, P. Kleihues, and H. Ohgaki, “IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas,” Clinical Cancer Research, vol. 15, no. 19, pp. 6002–6007, 2009. View at Publisher · View at Google Scholar · View at Scopus
  38. C.-L. Tso, P. Shintaku, J. Chen et al., “Primary glioblastomas express mesenchymal stem-like properties,” Molecular Cancer Research, vol. 4, no. 9, pp. 607–619, 2006. View at Publisher · View at Google Scholar · View at Scopus
  39. S. Paget, “The distribution of secondary growths in cancer of the breast,” The Lancet, vol. 133, no. 3421, pp. 571–573, 1889. View at Publisher · View at Google Scholar · View at Scopus
  40. G. Poste and I. J. Fidler, “The pathogenesis of cancer metastasis,” Nature, vol. 283, no. 5743, pp. 139–146, 1980. View at Publisher · View at Google Scholar · View at Scopus
  41. I. J. Fidler and G. Poste, “The ‘seed and soil’ hypothesis revisited,” The Lancet Oncology, vol. 9, no. 8, p. 808, 2008. View at Publisher · View at Google Scholar · View at Scopus
  42. B. H. Kong, N.-R. Park, J.-K. Shim et al., “Isolation of glioma cancer stem cells in relation to histological grades in glioma specimens,” Child's Nervous System, vol. 29, no. 2, pp. 217–229, 2013. View at Publisher · View at Google Scholar · View at Scopus
  43. E. Sulman, K. Aldape, and H. Colman, “Brain tumor stem cells,” Current Problems in Cancer, vol. 32, no. 3, pp. 124–142, 2008. View at Publisher · View at Google Scholar · View at Scopus
  44. K. B. Fallon, C. A. Palmer, K. A. Roth et al., “Prognostic value of 1p, 19q, 9p, 10q, and EGFR-FISH analyses in recurrent oligodendrogliomas,” Journal of Neuropathology and Experimental Neurology, vol. 63, no. 4, pp. 314–322, 2004. View at Publisher · View at Google Scholar · View at Scopus