Downregulation of the Yes-Associated Protein Is Associated with Extracellular Matrix Disorders in Ascending Aortic Aneurysms

Figure 2

(a, b) Western blotting showed that expression of YAP decreased significantly in the ascending aortic walls of patients with ascending aortic aneurysms compared to that of normal controls (). (c) Immunohistochemistry showed that YAP was weak in the ascending aortic walls of ascending aortic aneurysms relative to normal. (d) Confocal fluorescence microscopy showed that YAP and α-SMA double-staining cells were reduced in ascending aortic aneurysms.

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