The Immunomodulatory Effects of Mesenchymal Stem Cells in Prevention or Treatment of Excessive Scars

Figure 1

A summary of the immunomodulatory effects of MSCs that downregulate excessive scarring. MSCs are able to home the wound, where the stages of wound healing (inflammation, proliferation, and remodeling) are in progress. MSCs have been found to attenuate the activity of inflammatory cells, differentiate or transdifferentiate into epidermal cell lineages, escalate angiogenesis, and decrease fibrosis.