Heart-Derived Stem Cells in Miniature Swine with Coronary Microembolization: Novel Ischemic Cardiomyopathy Model to Assess the Efficacy of Cell-Based Therapy

Table 1

The effects of coronary microembolization on hemodynamics.

	Systolic pressure (mmHg)	Mean aortic pressure (mmHg)	Heart rate (bpm)	LVEDP (mmHg)	LV (mmHg/sec)	RPP
Baseline	135 ± 8	107 ± 6	86 ± 7	20 ± 3	2348 ± 64	11454 ± 731
1 hour	107 ± 12	83 ± 9	100 ± 7	18 ± 3	1336 ± 81	10728 ± 1317
2 months	144 ± 7	116 ± 6	77 ± 5	28 ± 3	1537 ± 33	10944 ± 599
3 months	140 ± 8	113 ± 7	88 ± 8	26 ± 2	1437 ± 184	12832 ± 1683

Values are mean ± SEM; versus baseline, LVEDP: left ventricular end-diastolic pressure, LV dP/dt: first derivative of LV pressure, and RPP: rate pressure product.