Heart-Derived Stem Cells in Miniature Swine with Coronary Microembolization: Novel Ischemic Cardiomyopathy Model to Assess the Efficacy of Cell-Based Therapy
Table 2
The effects of CDCs on hemodynamics.
Systolic pressure (mmHg)
Mean aortic pressure (mmHg)
Heart rate (bpm)
LVEDP (mmHg)
LV (mmHg/sec)
LV (mmHg/sec)
Untreated animals
Initial
144 ± 10
116 ± 7
77 ± 6
28 ± 3
1537 ± 40
−1964 ± 78
Final
140 ± 10
113 ± 8
88 ± 10
26 ± 3
1222 ± 126
−1510 ± 120
CDCs
Initial
127 ± 6
93 ± 5
69 ± 6
28 ± 2
1329 ± 103
−1969 ± 261
Final
133 ± 3
112 ± 4
85 ± 6
25 ± 2
1613 ± 90
−1525 ± 735
Values are mean ± SEM; LVEDP: left ventricular end-diastolic pressure; versus initial; versus untreated animals; untreated animals ; and CDCs .
