|
| Protein name | UniProtKB ID | Gene | Molecular function | Biological process | Subcellular location | Family | Function |
|
| Fibroblast growth factor-1 | P05230 | FGF1 | Developmental protein, growth factor, mitogen | Angiogenesis, differentiation | Cytoplasm, nucleus, secreted | Heparin-binding growth factors family | Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation, and cell migration |
|
| Granulocyte colony-stimulating factor | P09919 | CSF3 | Cytokine, growth factor | U/A | Secreted | IL-6 family | Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes, and the monocytes-macrophages |
|
| Granulocyte-macrophage colony-stimulating factor | P04141 | CSF2 | Cytokine, growth factor | U/A | Secreted | GM-CSF family | Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils, and erythrocytes |
|
| Pigment epithelium-derived factor | P36955 | SERPINF1 | U/A | U/A | Secreted | Serpin family | Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells |
|
| Metalloproteinase inhibitor 1 | P01033 | TIMP-1 | Growth factor, metalloenzyme inhibitor, metalloprotease inhibitor, and protease inhibitor | U/A | Secreted | Protease inhibitor I35 family | Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor |
|
| Plasminogen activator inhibitor 1 | P05121 | SERPINE1 | Protease inhibitor, serine protease inhibitor | U/A | Secreted | Serpin family | Serine protease inhibitor |
|
| Connective tissue growth factor | P29279 | CTGF | U/A | Cell adhesion, DNA synthesis | Extracellular matrix, secreted | CCN family | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes |
|
| Collagen alpha-2(I) chain | P08123 | COL1A2 | U/A | U/A | Extracellular matrix, secreted | Fibrillar collagen family | Type I collagen is a member of group I collagen (fibrillar forming collagen) |
|
| Collagen alpha-1(VI) chain | P12109 | COL6A1 | U/A | Cell adhesion | Extracellular matrix, secreted | Type VI collagen family | Collagen VI acts as a cell-binding protein |
|
| Fibronectin | P02751 | FN1 | U/A | Acute phase, angiogenesis, cell adhesion, and cell shape | Extracellular matrix, secreted | U/A | Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape |
|
