Research Article

Combined MSC and GLP-1 Therapy Modulates Collagen Remodeling and Apoptosis following Myocardial Infarction

Table 2

Changes in expression levels of genes involved in ECM remodeling one week after MI. Large changes in expression are demonstrated by arrows (↑ = 2–20x increase, ↑↑ = 20–50x increase.

Gene nameBeadsBeads-MSCBeads-MSC-GLP-1
InfarctBorderRemoteInfarctBorderRemoteInfarctBorderRemote

Col1a1
Col3a1
TIMP1
TIMP2↑↑
MMP2
MMP9↑↑ ↓↓
TGF-β