Stem Cells International / 2016 / Article / Fig 1

Research Article

Umbilical Cord Tissue-Derived Mesenchymal Stem Cells Induce T Lymphocyte Apoptosis and Cell Cycle Arrest by Expression of Indoleamine 2, 3-Dioxygenase

Figure 1

T lymphocyte inhibition potentials of 4 MSCs. (a) T lymphocytes proliferation was inhibited by MSCs in coculture. The data are expressed as the means ± SD from 5 independent experiments. The inhibitory effect of UC-MSC coculture groups on T lymphocytes proliferation was more prominent than that of the AT-, WJ-, and BM-MSC group. when compared to the BM-MSC. (b) T lymphocyte apoptosis induced by MSCs in coculture. The apoptotic ratio of UC-MSC coculture groups on T lymphocytes was much highly prominent compared to that of the AT-, WJ-, and BM-MSC group. (c) G0/G1 phase arrest of T lymphocytes induced by MSCs in coculture. The arrest effect of the UC-MSC coculture groups on T lymphocytes was more prominent than that of the AT-, WJ-, and BM-MSC group.
(a)
(b)
(c)

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.