In Vitro Expansion of Bone Marrow Derived Mesenchymal Stem Cells Alters DNA Double Strand Break Repair of Etoposide Induced DNA Damage

Figure 2

Viability of MSCs with passage following 24 hours of etoposide (VP16) exposure. MSCs at various passages were exposed to 25 μM VP16 for 24 hours and then allowed for 0, 6, or 48 hours to recover in fresh medium before evaluation of viability by Presto Blue viability reagent. Values are reported relative to untreated controls. indicates a significant decrease in viability relative to untreated control, Student’s -test; -value < 0.05.