Reprogramming of Melanoma Tumor-Infiltrating Lymphocytes to Induced Pluripotent Stem Cells

Figure 1

Freshly isolated CD8⁺ tumor-infiltrating lymphocytes (TILs) showed distinct phenotypical difference compared with CD8⁺ peripheral blood T cells (PBTCs). Phenotypic characterization of freshly isolated CD8⁺ T cells in TILs and PBTCs from patient (A) and patient (B). Expression of CCR7 and CD45RO (a) and PD-1, LAG-3, and TIM-3 (b) in CD8-gated live cells in TILs and PBTCs are shown. Number indicates the percentage of cells shown in each quadrant (a) or indicated gated regions (b).

(a)

(b)