Restoration of a Critical Mandibular Bone Defect Using Human Alveolar Bone-Derived Stem Cells and Porous Nano-HA/Collagen/PLA Scaffold

<div>Genetic stability evaluation. (a) The expression levels of p53, ARF, and c-myc in aBMSCs were unchanged over time and under osteogenic induction. (The term “induced” denotes aBMSCs at passage 3 that were cultured on nHAC/PLA scaffolds in osteogenic induction medium.) (b) aBMSCs at passage 4 that were cultured on nHAC/PLA in osteogenic induction medium exhibited a normal karyotype.</div>

Stem Cells International

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Figure 5

Figure 5: Restoration of a Critical Mandibular Bone Defect Using Human Alveolar Bone-Derived Stem Cells and Porous Nano-HA/Collagen/PLA Scaffold 