Comparison of Immunomodulation Properties of Porcine Mesenchymal Stromal/Stem Cells Derived from the Bone Marrow, Adipose Tissue, and Dermal Skin Tissue

<div>In vitro differentiation of passage 3 mesenchymal stromal/stem cells (MSCs). MSCs at ca. 80% confluence were subjected to osteogenic or adipogenic conditions, and differentiation was confirmed by staining with alizarin red S or oil red O solution, respectively. (A) MSCs were observed by both macrography before and after differentiation and micrography after differentiation showing A-MSCs, BM-MSCs, and DS-MSCs, respectively, derived from a female micropig. Scale bars = 200 <i>μ</i>m. MSCs were analyzed for the expression of osteogenesis- (<i>RUNX2</i> and<i> BGLAP</i>) and adipogenesis- (<i>PPARG</i> and<i> LPA</i>) related genes before (B) and at 1-week intervals after (C) differentiation. The housekeeping gene<i> GAPDH</i> was used as a control, shown in (B) and (C).</div>

Stem Cells International

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Figure 2: Comparison of Immunomodulation Properties of Porcine Mesenchymal Stromal/Stem Cells Derived from the Bone Marrow, Adipose Tissue, and Dermal Skin Tissue 

Figure 2 | Comparison of Immunomodulation Properties of Porcine Mesenchymal Stromal/Stem Cells Derived from the Bone Marrow, Adipose Tissue, and Dermal Skin Tissue 