Human Umbilical Cord Wharton Jelly-Derived Adult Mesenchymal Stem Cells, in Biohybrid Scaffolds, for Experimental Skin Regeneration

Figure 6

Full-skin restoration after the DE implant. (a, b) Magnification of H&E of the DE in comparison to that of the single wound at 21 and 36 days. The graph shows the values of epidermis thickness as a deviation from the normal value of the skin (z-scores), confirming the optimal healing of mouse epidermis treated with DE. within subjects and between subjects at the two analyzed times. (c, d) Magnification of Masson’s trichrome at 21 and 36 days to emphasize the presence and organization of the dermal collagen. (e) The average percentage of the collagen in the wound area and in the wound treated with DE at two times. is not significant. (f) Representative magnifications of H&E to highlight the neogenesis of progressive dermal annexes in the center of the wound treated with ED at various times.

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