From Blood to Lesioned Brain: An In Vitro Study on Migration Mechanisms of Human Nasal Olfactory Stem Cells

Figure 2

Bioinformatic analysis of the OE-MSC secretome. The 629 proteins secreted by OE-MSCs identified by mass spectrometry were analyzed using the Ingenuity Pathway software. (a) List of the five top canonical pathways, ranked by decreasing ratio values (percentage of identified secreted proteins in the pathway over a total of known proteins involved in this pathway). The numbers in the darker boxes indicate the number of OE-MSC-secreted proteins associated with the pathway; the number at the end of the bar represents the sum of known proteins associated with each specific pathway. (b) Schematic view of the 34 OE-MSC-secreted proteins involved in transmigration. The list of secreted proteins associated with cell movement and homing are found in Supplementary Table 1.

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