Stemness Characteristics of Periodontal Ligament Stem Cells from Donors and Multiple Sclerosis Patients: A Comparative Study

Figure 10

IPA network analysis. Peak scoring networks from NANOG, MEIS1, and SIX3, which regulate stemness properties, in P15 hPDLSCs (a) and P15 MS-hPDLSCs (b) are shown. Upregulated genes are shown in red. Downregulated genes are shown in green. Genes not existing in the LRG list but showed interaction with the LRG list are shown as white open nodes. A solid line depicts a direct functional interaction between the gene products. An arrow depicts functional target of the gene product. LRG: locus reference genomic sequence.

(a)

(b)