Review Article
Astrocytes at the Hub of the Stress Response: Potential Modulation of Neurogenesis by miRNAs in Astrocyte-Derived Exosomes
Table 3
miRNA associated with neurogenesis enriched in astrocytes derived exosomes.
| miRNA | Expression level | Cellular process | Molecular target | Reference |
| miR-25b | Overexpression | Promotes proliferation and differentiation of NSPCs | IGF signaling | [154] | miR-17-92 | Overexpression | Increase axonal outgrowth | PTEN | [123] | miR-92a | Upregulation/overexpression | Inhibits the transition from radial glial cells to intermediate progenitors | Tbr2 | [155] | miR-184 | Upregulation | Inhibits differentiation and promotes proliferation of NSPCs | Numbl | [156] | miR-302 | Upregulation | Block neural progenitor induction | BMP/TGFβ, NR2F2 | [157] | miR-96 | Upregulation | Block neural progenitor induction | PAX6 | [158] |
|
|