Review Article

Astrocytes at the Hub of the Stress Response: Potential Modulation of Neurogenesis by miRNAs in Astrocyte-Derived Exosomes

Table 3

miRNA associated with neurogenesis enriched in astrocytes derived exosomes.

miRNAExpression levelCellular processMolecular targetReference

miR-25bOverexpressionPromotes proliferation and differentiation of NSPCsIGF signaling[154]
miR-17-92OverexpressionIncrease axonal outgrowthPTEN[123]
miR-92aUpregulation/overexpressionInhibits the transition from radial glial cells to intermediate progenitorsTbr2[155]
miR-184UpregulationInhibits differentiation and promotes proliferation of NSPCsNumbl[156]
miR-302UpregulationBlock neural progenitor inductionBMP/TGFβ, NR2F2[157]
miR-96UpregulationBlock neural progenitor inductionPAX6[158]