miRNA associated with neurogenesis modified after different stimulus.
|miRNA||Expression level||Cellular process||Molecular target||Reference|
|miR-181a||Upregulated by morphine||Promote astrocyte-preferential differentiation of NSPCs||Prox1/Notch2|||
|miR-23b||Upregulated by morphine||Adult neurogenesis||Morphine receptor expression (MOR1)|||
|miR-190||Downregulated by fentanyl||Adult neurogenesis||NeuroD|||
|miR-143||Upregulation by IGF-1||Promotes proliferation, neural differentiation, and cell survival||PDGFRA, PRKCE, MAPK7, DSSP, DMP-1, KRAS, and BCL-2|||
|miR-181c||Upregulation by IGF1/LIF||Enhanced self-renewal of NSPCs||PTPN11, PTPN22, PTEN, Dusp6, PBX3, ZEB2, and IRF8|||