In Vitro and In Vivo Dentinogenic Efficacy of Human Dental Pulp-Derived Cells Induced by Demineralized Dentin Matrix and HA-TCP

Figure 4

Ectopic bone-forming efficacy of hDPSCs transplanted with HA-TCP or DDM in athymic nude mice. Bone formations in the transplantation of HA-TCP (a) and DDM (b) were analyzed by micro-CT. The results were shown as X-ray images (A) and 3D-visualization image (B). (c) Quantification of mineral volume change over 1 week and 8 weeks. 1, transplantation of HA-TCP only; 2, transplantation of HA-TCP with hDPSCs; 3, transplantation of DDM only; 4, transplantation of DDM with hDPSCs. Statistical analyses were carried out using Student’s t test. ; ; #, significant difference not be detected.

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