Stem Cells International

Research Article

Pulsed Electromagnetic Field Regulates MicroRNA 21 Expression to Activate TGF-β Signaling in Human Bone Marrow Stromal Cells to Enhance Osteoblast Differentiation

Table 6

Real-time RT-PCR analysis of three different female donor samples’ hBMSCs, aged 24, 27, and 31 years in the mineralization stage. Analysis by Student’s -test.
Gene symbolGene titleAverage PEMF/control %p
CDH11Cadherin 11, type 2, OB-cadherin (osteoblast)130 ± 36%
COL1A1Collagen, type I, alpha 1144 ± 47%
CXCL12Chemokine (C-X-C motif) ligand 12146 ± 20%
FBN2Fibrillin 2149 ± 54%
FOSBFBJ murine osteosarcoma viral oncogene homolog B165 ± 27%
GPC4Glypican 4128 ± 25%
IL8Interleukin 8162 ± 68%
LEPRLeptin receptor130 ± 19%
MMP16Matrix metallopeptidase 16 (membrane-inserted)135 ± 68%
SOX11SRY- (sex determining region Y-) box 11137 ± 37%
SPP1Secreted phosphoprotein 1132 ± 52%
TGFB2Transforming growth factor, beta 2128 ± 21%
TBRG1Transforming growth factor beta regulator 1113 ± 14%
THBS1Thrombospondin 1142 ± 58%