Research Article

Human Adipose-Derived Stem Cells Exhibit Enhanced Proliferative Capacity and Retain Multipotency Longer than Donor-Matched Bone Marrow Mesenchymal Stem Cells during Expansion In Vitro

Figure 3

qPCR analysis of senescence marker genes p16ink4a (a), p21 (b), and p53 (c) and pluripotency marker genes Nanog (d) and Oct-4 (e) in donor-matched MSCs and ASC at ELSC, MLSC, and LLSC. Data presented and relative gene expression normalised to the mean of the reference genes MRPL19 and EIF2B1 and plotted on a log scale (). Values are mean ± SEM. represents at MLSC or LLSC compared to ELSC. + represents in ASCs compared to MSCs at the same LSC.
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