Paracrine Secreted Frizzled-Related Protein 4 Inhibits Melanocytes Differentiation in Hair Follicle

Figure 2

The coexpression of sFRP4 and TRP1 in mouse and human HF and human skin. The right panel shows the enlarged view of the labeled area in the left panel. (a-b) sFRP4 is expressed in the hair matrix and HS precursors surrounding the TRP1 positive cells in both mouse (a) and human (b) HF. (c) sFRP4 is expressed in keratinocytes surrounding TRP1 positive cells in human skin. Bars: 50 um.

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