FGF2 Attenuates Neural Cell Death via Suppressing Autophagy after Rat Mild Traumatic Brain Injury

Figure 8

Rapamycin reversed the beneficial effects of FGF2 on neuronal survival and cell death after TBI. (a–c) Representative images of the ipsilateral cortex (left) and CA1 region of the ipsilateral hippocampus (right) on NeuN-stained, TUNEL-stained, and PI-stained coronal sections from each group 48 h post-TBI. Scale bar = 100 μm. (d–i) Quantitative analysis of the numbers of NeuN-positive, TUNEL-positive, and PI-positive cells in the ipsilateral cortex and CA1 region of the ipsilaterial hippocampus 48 h post-TBI in each group. The bars represent the mean ± SD. . versus TBI + vehicle and ^# versus TBI + FGF2.

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