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Stem Cells International
Volume 2017, Article ID 3167985, 12 pages
https://doi.org/10.1155/2017/3167985
Research Article

The Impact of GFP Reporter Gene Transduction and Expression on Metabolomics of Placental Mesenchymal Stem Cells Determined by UHPLC-Q/TOF-MS

1State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China
2Collaborative Innovation Center for the Diagnosis and Treatment of Infectious Diseases, Zhejiang University, Hangzhou 310003, China
3Department of Chemistry, University of Alberta, Edmonton, AB, Canada T6G 2G2
4Chu Kochen Honors College, Zhejiang University, 866 Yuhangtang Rd., Hangzhou 310058, China

Correspondence should be addressed to Hongcui Cao; nc.ude.ujz@oacch

Received 24 April 2017; Revised 23 July 2017; Accepted 7 August 2017; Published 5 November 2017

Academic Editor: Yonglun Luo

Copyright © 2017 Jinfeng Yang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplemental Table S1A. Identification of cellular metabolites based on the mass and retention time matches against the dansyl standard library. Supplemental Table S1B. Identification of cellular metabolites by searching the accurate mass of the peak pairs against the HMDB library. Supplemental Table S1C. Identification of cellular metabolites by searching the accurate mass of the peak pairs against the EML library with one reaction in MCID.Figure S1. The Venn diagram shows the numbers of peak pairs detected using 9/1 MeOH/CHCl3 (method 1) and 1/1 MeOH/H2O (method 2) as extraction solvent respectively.

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